1947: The Institute for Sex Research, popularly known as the Kinsey Institute after researcher Alfred C. Kinsey, is incorporated in Indiana.

1990: After a five-year, highly publicized battle with AIDS, Ryan White, eighteen, dies of the disease in a hospital in Indianapolis, one month before his high school graduation.  White, a hemophiliac, had contracted the disease through a contaminated blood treatment and went on to become a poster child during the early years of the AIDS epidemic, changing the public perception of the disease.